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The Global effects of Antimicrobial Resistance (AMR) are well documented, but reliable estimates of the true burden are scarce. The AMR challenges are numerous and complex, but Evotec are confronting the renewed challenge with innovative thinking, creativity and novel approaches in both target and technology.
In this webcast we outline our most recent work in antibacterial discovery, combining innovation, integration and efficiency with operation excellence to develop leading edge platforms:
- The application of machine learning to optimise chemical matter - combining biological data, medical chemistry expertise and a deep learning approach
- The Vivo Mimetic Media (VMM) concept for discovering novel Gram Negative antibacterials
- The use of luminescent or fluorescent bacteria in PD models
- The In vitro PK/PD Hollow Fibre Infection Model, providing an understanding of the effect of drug treatment on a chosen microbial population
About the Speaker
Dr Antonio Felici PhD
VP Anti-Infectives, AMR Therapeutic Area Lead
Antonio coordinates the group effort in Infectious Disease across multiple Evotec sites. He holds a PhD in Enzymology and Applied Biochemistry from the Centre of Protein Engineering of University of Liège, Belgium and has more than 25 years Industry experience in Drug Discovery & Development in Antibacterial research. Over this period, he led and collaborated on antibacterial project teams, which designed, identified and progressed novel compounds through development into the clinic and in recent years established successful and productive growing collaborations with different Biotech and Pharma industries.
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